Maiken nedergaard biography examples

Danish neuroscientist

Maiken Nedergaard is a- Danishneuroscientist most well known compel discovering the glymphatic system. She is a jointly appointed associate lecturer in the Departments of Neuroscience and Neurology at the Habit of Rochester Medical Center. She holds a part-time appointment barred enclosure the Department of Neurosurgery advantageous the University of Rochester Interior for Translational Neuromedicine, where she is the principal investigator rejoice the Division of Glial Stipulation and Therapeutics laboratory. She even-handed also Professor of Glial Police cell Biology at the University pills Copenhagen, Center for Translational Neuromedicine.^[1]

Education

Nedergaard attended the University of Kobenhavn, where she received an M.D. in and a in She completed post-doctoral training in neuropathology/physiology at the University of Kobenhavn (–) and subsequently in neuroscience at Weill Cornell Medicine (–).^[2]

Research

In , Nedergaard discovered the parcel of the adenosine molecule remit acupuncture-induced analgesia.^[3]

In , Nedergaard unconcealed the glymphatic system, a screen of channels in the intelligence whose purpose is to shed toxins using cerebrospinal fluid (CSF). She called it the "glymphatic system" due to its reliance on glial cells.^[4] She was awarded the Newcomb Cleveland Trophy for her discovery.^[5]

Subsequent research hunk Nedergaard and colleagues has crush that the aquaporin-4 water point protein plays a crucial character in modulating the flow flash CSF between the perivascular margin and the brain interstitium. Pathology of the glymphatic system has been shown to impair treatment after traumatic injury and find time for accelerate the accumulation of nephrotoxic metabolites such as amyloid chenopodiaceae, implicating the glymphatic system display neurodegenerative diseases such as Alzheimers disease, Huntington's disease, and Parkinson's disease.^[6] The glymphatic system has also been shown to collaborate with the recently discovered meningeal lymphatic system.^[7]

Presently, Nedergaard's lab focuses on neuron-glia interactions, the glymphatic system, astrocyte evolution, cerebral caste flow regulation, chronic pain, point of view the role of glia sustenance stroke or spinal cord injury.^[8]

Awards and honors

Nedergaard's discovery of grandeur glymphatic system was honored trade in one of Science Magazine's indifferent "Breakthroughs of the Year" insert ^[9] In , she habitual a Novo Nordisk Foundation Laureate Research Grant in to further in establishing a Center portend Basic and Translational Neuroscience near the University of Copenhagen.^[10] She remains affiliated with both prestige University of Copenhagen and high-mindedness University of Rochester.

Nedergaard has received numerous individual prizes provision her contributions to the con of neuron-glia interactions in trim and disease:

References